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主营:激酶、磷酸二酯酶、磷酸酶、组蛋白去甲基化酶、组蛋白甲基化转移酶、HDACs、聚ADP核糖聚合酶
℡ 4000-520-616
℡ 4000-520-616
Bpsbioscience/UBE2O, GST-Tag/79374/10 µg
产品编号:79374
市  场 价:¥6200.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$310.00
品      牌: BPS Bioscience
公      司:BPS Bioscience Inc.
公司分类:
Bpsbioscience/UBE2O, GST-Tag/79374/10 µg
商品介绍
Species: Human
Host Species: Sf9 insect cells using baculovirus
MW: ~90 kDa
Genbank #: BC022237
Tag(s): N-terminal GST-Tag
Background:
UBE2O or ubiquitin-conjugating enzyme E2O is a part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin. HIV-1 Tat has been identified to have a physical interaction with ubiquitin-conjugating enzyme E2O (UBE2O) in human HEK293 and Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses (1).
Description:
Recombinant full-length human UBE2O, also known as E2-230K, FLJ12878, and KIAA1734. Genbank Accession BC022237 with an N-terminal GST tag, expressed in Sf9 cells via a baculovirus expression system. MW = 90kDa.
Synonym(s):
E2-230K, FLJ12878, KIAA1734
Formulation:
50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Storage / Stability:

At least 6 months at –80°C. Avoid freeze/thaw cycles.

Application(s):
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s):

1. Rumbaugh JA. et.al. Neurobiol Dis, 2012 Aug 25. 

Warning(s):
Avoid freeze/thaw cycles
Scientific Category:
Ubiquitination
Product Type:
Activating Enzyme
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍

BPS bioscience总部坐落于世界最大之一的美国圣地亚哥生命科学研究机构和公司集中地的中心。公司主要提供激酶、磷酸二酯酶、磷酸酶、组蛋白去甲基化酶、组蛋白甲基化转移酶、HDACs、聚ADP核糖聚合酶。BPS公司为药物研发用重组酶类的提供了最大选择之一。产品类型 重组酶类;分子细胞生物学;重组蛋白;分析试剂盒;底物;重组细胞系

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