Human TRKC, also known as NTKR3 (Neurotrophic Tyrosine Kinase Receptor, type 3) or NT-3 Receptor, GenBank Accession No. NM_002530, a.a. 456-825(end), with N-terminal GST-tag, MW=68 kDa, expressed in Sf9 cells via a baculovirus expression system.
UniProt
Q16288
Synonym(s):
TRKC, NTKR3, NT-3 Receptor, Neurotrophic Tyrosine Kinase Receptor, type 3
Specific Activity:
1.0 pmol/min/μg
Assay Conditions:
Activity determined using a DELFIA-assay with a poly-(Glu:Tyr 4:1)-biotin-coated plate, for 30 min. at room temperature.
Formulation:
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 3 mM DTT, and 20% glycerol
Format:
Aqueous buffer solution
Storage / Stability:
>6 months at –80°C.
Application(s):
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s):
1. Lamballe, F., et al. (1991). Cell 66 (5): 967–979. 2. Tessarollo, L., et al. (1993). Development 118 (2): 463–75. 3. McGregor, L.M., et al. (1994). Genomics 22 (2): 267–72.
Warning(s):
Avoid freeze/thaw cycles
Scientific Category:
Kinase/Receptor Tyrosine
Product Type:
Recombinant Protein
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