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主营:激酶、磷酸二酯酶、磷酸酶、组蛋白去甲基化酶、组蛋白甲基化转移酶、HDACs、聚ADP核糖聚合酶
℡ 4000-520-616
℡ 4000-520-616
Bpsbioscience/JMJD2C(KDM4C), GST-tag/50105/100 µg
产品编号:50105
市  场 价:¥9300.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$465.00
品      牌: BPS Bioscience
公      司:BPS Bioscience Inc.
公司分类:
Bpsbioscience/JMJD2C(KDM4C), GST-tag/50105/100 µg
商品介绍
Species: Human
Host Species: Sf9 insect cells
MW: 69 kDa
Genbank #: BC143571
Tag(s): N-terminal GST-tag
a.a: 2–372
Description:
Human JMJD2C (GenBank Accession No. BC143571) (a.a. 2-372) with N-terminal GST-tag, MW=69 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
UniProt
Q9H3R0
Synonym(s):
KDM4C, GASC1
Specific Activity:
0.17 pmole/min/μg
Assay Conditions:
0.5 µM of 3MeK9 H3 1-21[B]; 1 hr incubation at RT; 5 uL of anti-mouse acceptor beads (1:250 dilution) + 5 uL of primary ab 5 (1:100 dilution) incubate at RT for 30 min; 10 uL of streptavidin donor beads (1:125) for 30 min; read alpha counts.
Formulation:
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% glycerol, and 16 mM glutathione
Format:
Aqueous buffer solution
Storage / Stability:

>6 months at –80°C.

Application(s):
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s):

1. Vinatzer, U., et al., Clin Cancer Res. 2008 Oct 15;14(20):6426-31.
2. Pollard, P.J., et al., Biochem J. 2008 Dec 15;416(3):387-94.

Application Reference(s):
A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth (2013)

Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
Demethylase
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍

BPS bioscience总部坐落于世界最大之一的美国圣地亚哥生命科学研究机构和公司集中地的中心。公司主要提供激酶、磷酸二酯酶、磷酸酶、组蛋白去甲基化酶、组蛋白甲基化转移酶、HDACs、聚ADP核糖聚合酶。BPS公司为药物研发用重组酶类的提供了最大选择之一。产品类型 重组酶类;分子细胞生物学;重组蛋白;分析试剂盒;底物;重组细胞系

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