Human polybromo 1 (PB1), also known as PBRM1 and BRG1-associated factor 180, variant 2, GenBank Accession No. NM_018313, a.a. 528 – 618 corresponding to bromodomain 4 with N-terminal His-tag, MW = 11.7 kDa, expressed in an E. coli cell expression system.
UniProt
Q86U86
Synonym(s):
PBRM1, BRG1-associated factor 180
Formulation:
50 mM Tris-HCl, pH 8.0, 150 mM NaCl, and 10% glycerol.
Format:
Aqueous buffer solution
Storage / Stability:
>6 months at –80°C.
Application(s):
Useful for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling.
Reference(s):
1. Sekine, I., et al., Oncogene. 2005 Apr 14;24(16):2735-8. 2. Shibata, Y., et al., Dev Biol. 2012 Jan 15;361(2):349-57.
Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
Bromodomain
Product Type:
Recombinant Protein
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