Bpsbioscience/Mouse FLT3 Ligand/90136-A/2 µg,BPS Bioscience,,BPS Bioscience,bpsbioscience,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Bpsbioscience/Mouse FLT3 Ligand/90136-A/2 µg

产品编号：90136-A

市场价：¥2600.00

场地：美国(厂家直采)

产品分类：蛋白类>重组蛋白>细胞因子>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$130.00

品牌： BPS Bioscience

公司：BPS Bioscience Inc.

公司分类：

商品介绍

Species: Mouse

Host Species: E. coli

MW: 32 kDa

Genbank #: P49772

a.a: 27–189

Background:

FLT-3 ligand promotes long- term expansion and differentiation of human pro-B-cells in the presence of IL-7 or in combination of IL-7 and IL-3.The human FLT-3 ligand also stimulates the proliferation of cells expressing murine FLT-3 receptors. In combination with SCF and IL-3, FLT-3 ligand can cause expansion of cells with the marker spectrum CD34(+) CD38(-). Alone, FLT-3 ligand supports the survival of precursors in the lineage of blood-forming cells such as CFU-GM, CFU- GEMM, and the very primitive high proliferative potential colony-forming cells, HPP- CFC. flt-3 ligand only has marginal effects on progenitors for erythroid cells and megakaryocytes.

Description:

Recombinant FLT-3 Ligand is a disulfide-linked monomer protein consisting of 164 amino acid residues, and migrates as an approximately 32 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding mouse FLT-3 ligand mature chain was expressed in E. coli.

UniProt

P49772

Synonym(s):

Fms-Related Tyrosine Kinase 3 Ligand, FLT3L, CD135L

Purity:

≥95% by SDS-PAGE and HPLC

Endotoxin Level:

<0.1 ng/µg (1 EU/µg), using the LAL gel clot method.

Biological Activity:

The ED₅₀ was determined by the dose-dependent proliferation of human AML5 cells to be in the range of 10.0 ng/ml.

Formulation:

Lyophilized from 0.2 µm filtered solution with 50 mM Tris, 100 mM NaCl, pH 8.5.

Format:

lyophilized protein

Reconstitution:

Reconstitute at 0.1-1.0 mg/ml in distilled water. This solution can then be diluted into other buffers. To maximize product collection from vial surface, vortex briefly and then spin down to recollect the liquid.

Storage / Stability:

The lyophilized protein is stable for at least 2 years from date of receipt when stored at -20°C. Upon reconstitution, store in working aliquots at +4°C for up to one month, or at -20°C for up to six months, in the presence of a carrier protein. Avoid repeated freeze/thaw cycles.

Reference(s):

1. Cancer Res. 2009 Oct 1,69(19):7747-55.
2. Blood, Jul 2009, 114: 835 - 843.
3. J. Immunol., Jun 2009, 182: 7408 - 7414.

Warning(s):

Avoid freeze/thaw cycles

Amino Acid Sequence:

GTPD CYFSHSPISS NFKVKFRELT DHLLKDYPVT VAVNLQDEKH CKALWSLFLA QRWIEQLKTV AGSKMQTLLE DVNTEIHFVT SCTFQPLPEC LRFVQTNISH LLKDTCTQLL ALKPCIGKAC QNFSRCLEVQ CQPDSSTLLP PRSPIALEAT ELPEPRPRQ

Scientific Category:

Cytokine/Growth Factors

Product Type:

Recombinant Protein

Data shown is lot-specific. Contact us for specific information on other lots.

品牌介绍

BPS bioscience总部坐落于世界最大之一的美国圣地亚哥生命科学研究机构和公司集中地的中心。公司主要提供激酶、磷酸二酯酶、磷酸酶、组蛋白去甲基化酶、组蛋白甲基化转移酶、HDACs、聚ADP核糖聚合酶。BPS公司为药物研发用重组酶类的提供了最大选择之一。产品类型重组酶类；分子细胞生物学；重组蛋白；分析试剂盒；底物；重组细胞系

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