Bpsbioscience/Human Resistin/90233-A/5 µg,BPS Bioscience,,BPS Bioscience,bpsbioscience,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Bpsbioscience/Human Resistin/90233-A/5 µg

产品编号：90233-A

市场价：¥2600.00

场地：美国(厂家直采)

产品分类：蛋白类>重组蛋白>细胞因子>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$130.00

品牌： BPS Bioscience

公司：BPS Bioscience Inc.

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商品介绍

Species: Human

Host Species: E. coli

MW: 10 kDa

Genbank #: Q9HD89

a.a: 17–108

Background:

Resistin was identified by screening for genes that are induced during the differentiation of adipocytes but down-regulated in mature adipocytes. Resistin gene expression is induced during the differentiation of adipocytes. Resistin circulates in mouse serum, and its level is increased markedly in obesity. Adipocytes secrete resistin as a unique signaling molecule that may be the hormone potentially linking obesity to type II diabetes, which is characterized by target-tissue resistance to insulin. TNF-alpha is a negative regulator of Resistin gene expression and inhibits Resistin mRNA expression and protein secretion by 70-90% in 3T3-L1 adipocytes.

Description:

Recombinant Resistin is a disulfide-linked homodimeric protein consisting of two 93 amino acid residues, and migrates as an approximately 20 kDa protein under non-reducing conditions and as a 10 kDa protein under reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Resistin mature chain was expressed in E. coli.

UniProt

Q9HD89

Synonym(s):

Resistin, FIZZ3, Adipose Tissue-Specific Secretory Factor, ADSF, XCP1

Purity:

≥95% by SDS-PAGE and HPLC

Endotoxin Level:

<0.1 ng/µg (1 EU/µg), using the LAL gel clot method.

Biological Activity:

Determined by its ability to stimulate lipolysis in cultured human adipocytes.

Formulation:

Lyophilized from a 0.2 µm filtered PBS solution.

Format:

lyophilized protein

Reconstitution:

Reconstitute at 0.1-1.0 mg/ml in distilled water. This solution can then be diluted into other buffers. To maximize product collection from vial surface, vortex briefly and then spin down to recollect the liquid.

Storage / Stability:

The lyophilized protein is stable for at least 2 years from date of receipt when stored at -20°C. Upon reconstitution, store in working aliquots at +4°C for up to one month, or at -20°C for up to six months, in the presence of a carrier protein. Avoid repeated freeze/thaw cycles.

Reference(s):

1. Al-Suhaimi EA, Shehzad A. Eur J Med Res. 2013 May 1,18:12.
2. Lee SE, Kim HS. J Smooth Muscle Res. 2012,48(1):27-35.
3. Tiaka EK, et al. Cytokine Growth Factor Rev. 2011 Apr,22(2):109-19.

Warning(s):

Avoid freeze/thaw cycles

Amino Acid Sequence:

SSKTLCSMEEAINERIQEVAGSLIFRAISSIGLECQSVTSRGDLATCPRGFAVTGCTCGSACGSWDVRAETTCHCQCAGMDWTGARCCRVQP

Scientific Category:

Cytokine/Growth Factors

Product Type:

Recombinant Protein

Data shown is lot-specific. Contact us for specific information on other lots.

品牌介绍

BPS bioscience总部坐落于世界最大之一的美国圣地亚哥生命科学研究机构和公司集中地的中心。公司主要提供激酶、磷酸二酯酶、磷酸酶、组蛋白去甲基化酶、组蛋白甲基化转移酶、HDACs、聚ADP核糖聚合酶。BPS公司为药物研发用重组酶类的提供了最大选择之一。产品类型重组酶类；分子细胞生物学；重组蛋白；分析试剂盒；底物；重组细胞系

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