Nucleosomes prepared from
mammalian HEK293 cells as a substrate for
histone methyltransferase assay.
Formulation:
10 mM Tris-HCl, pH 7.2, 5
mM NaCl, 1 mM MgCl2, 0.5 mM CaCl2, 125
mM EDTA, and 10 mM Sodium Butyrate
Format:
Aqueous buffer solution
Storage / Stability:
At least 6 months at –80°C.
Application(s):
Substrate for histone methyltransferase assays. Ideal for screening small molecular inhibitors of histone methyltransferases for drug discovery and HTS applications.