Bpsbioscience/Histone H3/H4 Tetramer (full length), His-tag/52064-2/100 µg,BPS Bioscience,,BPS Bioscience,bpsbioscience,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Bpsbioscience/Histone H3/H4 Tetramer (full length), His-tag/52064-2/100 µg

产品编号：52064-2

市场价：¥9100.00

场地：美国(厂家直采)

产品分类：蛋白类>重组蛋白>细胞因子>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$455.00

品牌： BPS Bioscience

公司：BPS Bioscience Inc.

公司分类：

商品介绍

Species: Human

Host Species: E. coli

MW: 57 kDa

Genbank #: NM_003532, NM_003548

Tag(s): N-terminal His-tag

Background:

The histone tetramer consists of two copies of both histones H3 and H4. It forms the central core of the nucleosome and, as such, plays a prominent role in the assembly, disassembly and positioning of nucleosomes.

Description:

Human recombinant histone tetramer, full length, consisting of 2 molecules each of histones H3 (a.a. 1-136(end)), and H4 (a.a. 1-103(end)), each with an N-terminal His-tag, expressed in an E. coli expression system. GenBank Accession Nos. are NM_003532, and NM_003548, respectively. Global MW = 57 kDa.

UniProt

P68431, P62805

Synonym(s):

H3/H4

Formulation:

45 mM Tris pH 7.5, 2 M NaCl, 1 mM EDTA, 1 mM DTT and 10% glycerol.

Format:

Aqueous buffer solution

Storage / Stability:

>6 months at –80°C

Application(s):

Substrate for histone methyltransferase or acetyltransferase assays. Ideal for screening small molecular inhibitors of histone methyltransferases and acetyltransferases for drug discovery and HTS applications.

Reference(s):

1. Huang, C., et al., PLoS Genet. 2013; 9(6): 1371.
2. Liu, W.H., et al., Nucleic Acids. 2012; 40(22):11229-39

Notes:

Since the recombinant histone proteins in this tetramer were prepared in E. coli, they will not have methyl, acetyl or many other epigenetic marks.

Warning(s):

Avoid freeze/thaw cycles

Scientific Category:

Methyltransferase

Product Type:

Substrate

Data shown is lot-specific. Contact us for specific information on other lots.

品牌介绍

BPS bioscience总部坐落于世界最大之一的美国圣地亚哥生命科学研究机构和公司集中地的中心。公司主要提供激酶、磷酸二酯酶、磷酸酶、组蛋白去甲基化酶、组蛋白甲基化转移酶、HDACs、聚ADP核糖聚合酶。BPS公司为药物研发用重组酶类的提供了最大选择之一。产品类型重组酶类；分子细胞生物学；重组蛋白；分析试剂盒；底物；重组细胞系

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