Bpsbioscience/Human Growth Hormone 192AA/90142-A/100 µg,BPS Bioscience,,BPS Bioscience,bpsbioscience,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Bpsbioscience/Human Growth Hormone 192AA/90142-A/100 µg

产品编号：90142-A

市场价：¥2600.00

场地：美国(厂家直采)

产品分类：蛋白类>重组蛋白>细胞因子>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$130.00

品牌： BPS Bioscience

公司：BPS Bioscience Inc.

公司分类：

商品介绍

Species: Human

Host Species: E. coli

MW: 22 kDa

Genbank #: P01241

a.a: 27–217

Background:

The physiological activity for which growth hormone is best known is the promotion of growth of bone, cartilage, and soft tissues. Detectable levels of growth hormone are found throughout the remainder of adulthood, suggesting other functions in addition to promotion of growth. Growth hormone may be important for the maintenance of lean body mass, most growth-promoting effects of growth hormone are mediated by IGF-1 the synthesis of which is regulated by growth hormone. The biological activities of growth hormone are mediated by receptors belonging to one of the cytokine receptor families. Growth hormone has been shown to be produced by T- cells, B-cells, and macrophages. In human lymphocytes, growth hormone appears to up-regulate its own expression. Growth hormone appears to act as an enhancer of immune responses and is produced in considerable amounts by T- helper cells.

Description:

Recombinant human growth hormone is a disulfide-linked monomeric protein consisting of 192 a.a. and migrates as an approximately 22 kDa protein under reducing and non-reducing conditions. Optimized DNA sequence encoding human growth hormone mature chain was expressed in E. coli.

UniProt

P01241

Synonym(s):

growth hormone, GH1, Somatotropin

Purity:

≥95% by SDS-PAGE and HPLC

Endotoxin Level:

<0.1 ng/µg (1 EU/µg), using the LAL gel clot method.

Biological Activity:

Determined by a dose-dependent cell proliferation assay using the rat lymphoma, Nb2-11, to be in the range of 0.1 ng/ml.

Formulation:

Lyophilized from a 0.2 µm filtered solution of 5 µM NaHCO₃, pH 10.

Format:

lyophilized protein

Reconstitution:

Reconstitute at 0.1-1.0 mg/ml in distilled water. This solution can then be diluted into other buffers. To maximize product collection from vial surface, vortex briefly and then spin down to recollect the liquid.

Storage / Stability:

The lyophilized protein is stable for at least 2 years from date of receipt when stored at -20°C. Upon reconstitution, store in working aliquots at +4°C for up to one month, or at -20°C for up to six months, in the presence of a carrier protein. Avoid repeated freeze/thaw cycles.

Reference(s):

1. Pediatrics. Nov. 2010, 126(5): e1211-26.
2. Handbook Exp. Pharmacol. 2010, (195):187-200.
3. Horm Res. Nov. 2009, 72 Suppl 1: 60-4.

Warning(s):

Avoid freeze/thaw cycles

Amino Acid Sequence:

FPTI PLSRLFDNAM LRAHRLHQLA FDTYQEFEEA YIPKEQKYSF LQNPQTSLCF SESIPTPSNR EETQQKSNLE LLRISLLLIQ SWLEPVQFLR SVFANSLVYG ASDSNVYDLL KDLEEGIQTL MGRLEDGSPR TGQIFKQTYS KFDTNSHNDD ALLKNYGLLY CFRKDMDKVE TFLRIVQCRS VEGSCGF

Scientific Category:

Cytokine/Growth Factors

Product Type:

Recombinant Protein

Data shown is lot-specific. Contact us for specific information on other lots.

品牌介绍

BPS bioscience总部坐落于世界最大之一的美国圣地亚哥生命科学研究机构和公司集中地的中心。公司主要提供激酶、磷酸二酯酶、磷酸酶、组蛋白去甲基化酶、组蛋白甲基化转移酶、HDACs、聚ADP核糖聚合酶。BPS公司为药物研发用重组酶类的提供了最大选择之一。产品类型重组酶类；分子细胞生物学；重组蛋白；分析试剂盒；底物；重组细胞系

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