Bpsbioscience/Z-WEHD-FMK/27672-1/5 mg,BPS Bioscience,,BPS Bioscience,bpsbioscience,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Bpsbioscience/Z-WEHD-FMK/27672-1/5 mg

产品编号：27672-1

市场价：¥4400.00

场地：美国(厂家直采)

产品分类：蛋白类>重组蛋白>细胞因子>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$220.00

品牌： BPS Bioscience

公司：BPS Bioscience Inc.

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商品介绍

MW: 76.8 Da

CAS Registry #: 210345-00-9

Formula: C₃₇H₄₂FN₇O₁₀

Target: caspase-5

Background:

Since caspase-14 also recognizes this WEHD substrate, this inhibitor may also show inhibition of caspase-14 activity.

Description:

A cell permeable, synthetic peptide that irreversibly inhibits certain caspases. It is selective for caspase-5, but also shows some inhibition of caspase-1 and cathepsin B (IC50 = 6 µM).

Biological Activity:

We recommend using 2-10 µM for inhibiting caspase activity in cell culture. The optimal dose may vary for different cells and culture conditions.

Solubility:

Soluble in DMSO

Storage / Stability:

Store at or below +4°C. Solid form is stable at least 12 months from date of receipt, when stored as directed.

Reference(s):

1. Heuer, D., et al. Nature, 457, 2009
2. Kamada, S., Fet al. (1997) Cell Death Diff. 4, 473-478.
3. Park, K., et al. Biochem Biophys Res Commun. 2006 Sep 8;347(4):941-8.

Notes:

The inhibitor is designed as a methyl ester to facilitate cell permeability. If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups.

Amino Acid Sequence:

Z-Trp-Glu(OMe)-His-Asp(OMe)-FMK

Scientific Category:

Apoptosis Inhibitor

Product Type:

Inhibitor

Data shown is lot-specific. Contact us for specific information on other lots.

品牌介绍

BPS bioscience总部坐落于世界最大之一的美国圣地亚哥生命科学研究机构和公司集中地的中心。公司主要提供激酶、磷酸二酯酶、磷酸酶、组蛋白去甲基化酶、组蛋白甲基化转移酶、HDACs、聚ADP核糖聚合酶。BPS公司为药物研发用重组酶类的提供了最大选择之一。产品类型重组酶类；分子细胞生物学；重组蛋白；分析试剂盒；底物；重组细胞系

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