Incooperationwithotherchaperones,Hsp70st
ABIlizespreexistentproteinsagainstaggregationandmediatethefoldingofnewlytranslatedpolypeptidesinthecytosolaswellaswithinorganelles.Thesechaperonesparticipateinalltheseprocessesthroughtheirabilitytorecognizenonnativeconformationsofotherproteins.Theybindextendedpeptidesegmentswithanethydrophobiccharacterexposedbypolypeptidesduringtranslationandmembranetranslocation,orfollowingstress-induceddamage.